Glucose concentrations in the plasma during pregnancy

Guidelines of the German Federal Committee of Physicians and Health Insurers on Medical Care during Pregnancy and after Childbirth.

In the amended „Guidelines of the German Federal Committee of Physicians and Health Insurers on Medical Care during Pregnancy and after Childbirth” that came into force on 3 March 2012, determining the concentration of glucose in the plasma was once again included. The test to determine it is carried out between the 24th (+ 0) and 27th (+ 6) week of pregnancy, one hour after oral administration of 50 g of glucose solution (regardless of the time of the last meal, i.e. the patient should not be fasting).

Pregnant women with blood sugar values between 7.5 mmol/l (135 mg/dl = no GDM) and 11.1 mmol/l (200 mg/dl = GDM) should promptly be given a further oral glucose tolerance test (OGTT) with 75 g of glucose solution after fasting from food for at least 8 hours.

Reference ranges
Limit values for the screening test with 50 g of glucose:
After 1 hour: < 7.5 mmol/l (135 mg/dl)

Limit values for OGTT during pregnancy:
Fasting: < 5.1 mmol/l (92 mg/dl)
After 1 hour: < 10.0 mmol/l (180 mg/dl)
After 2 hours: < 8.5 mmol/l (153 mg/dl)
According to IADPSG Consensus recommendations

Test material
Venous blood (NaF/citrate plasma)

If one or more of the values listed above are exceeded, further treatment of the pregnant woman should be carried out in close cooperation with a medical practice that is qualified in diabetology. When making the decision concerning subsequent treatment, possible ways of reducing risk through increased physical activity and adapting the diet should be included.


Literature and source
This information is based on the practice guideline of the German Diabetes Society (DGG) and the German Society of Gynaecology and Obstetrics (DGGG). First published in 10/2011, last updated in 8/2012.

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